Some Fixed Point Theorems in Generalized Dislocated Metric Spaces

The notion of a generalized dislocated metric space is introduced, its topological properties are established and an analogue of seghals fixed point theorem is obtained from which existence and uniqueness of fixed points for self maps that satisfy the metric analogues of contractive conditions mentioned and it can be derived. Keywords: Generalized dislocated metric, Kuratowski's axioms, coincidence point, Contractive conditions

On Generalized Dislocated Quasi Metrics

The notion of dislocated quasi metric is a generalization of metric that retains, an analogue of the illustrious Banach's Contraction principle and has useful applications in the semantic analysis of logic programming. In this paper we introduce the concept of generalized dislocated quasi metric space.The purpose of this note is to study topological properties of a metric, its connection with generalized dislocated metric space and to derive some fixed point theorems. Keywords: Generalized dislocated metric, Generalized dislocated quasi metric, Contractive conditions, coincidence point, b-property

Three dimensional elasticity solutions of sandwich panels using the extended Kantorovich method

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STUDY OF URINARY TRACT INFECTIONS IN TERTIARY CARE HOSPITAL EMPHASIZING ON BACTERIOLOGICAL PROFILE WITH ANTIBIOGRAM.

The present study was carried out to analyse the culture reports 470 urine samples collected from symptomatic patients between 18 to 80 years from department of medicine, surgery and gynaecology from May 2017 to 0ctober 2017. All the samples collected during the above period were subjected for culture sensitivity as per standard methods. The most common infection encountered in clinical practice is urinary tract infection. Urinary tract infection can be caused by different microorganisms including bacteria, parasites, fungi and viruses which are the major causative organisms. Among these, bacteria account for more than 95% of Urinary tract infection cases. Escherichia coli is the commonest urinary pathogen accounting for over 80% of community acquired infection. In this study the most common pathogenic organism isolated was Escherichia coli 44(55.69%) followed by Staphylococcus aureus 20(25.31%) and Klebsiella species 11(13.92%) in both males and females. Escherichia coli were sensitive to nitrofurantoin, amikacin and piperacillin tazobactam in 35 (79.4%), 25(56.81%) and 18(40.95%) respectively. Similarly 16(80%) of Staphylococcal isolates were sensitive to nitrofurantoin 11(55%) to amikacin and 5(25%) to piperacillin tazobactam. Klebsiella isolates also showed highest sensitivity to nitrofurantoin and piperacillin tazobactam 7(63%) followed by ceftriaxone 6 ( 54%.) This study will help clinicians to choose the right empirical antibiotics, and they should take into account the local sensitivity and resistance patterns while prescribing empirical oral or intravenous antibiotics

Mechanisms of Cellular Senescence: Cell Cycle Arrest and Senescence Associated Secretory Phenotype

Cellular senescence is a stable cell cycle arrest that can be triggered in normal cells in response to various intrinsic and extrinsic stimuli, as well as developmental signals. Senescence is considered to be a highly dynamic, multi-step process, during which the properties of senescent cells continuously evolve and diversify in a context dependent manner. It is associated with multiple cellular and molecular changes and distinct phenotypic alterations, including a stable proliferation arrest unresponsive to mitogenic stimuli. Senescent cells remain viable, have alterations in metabolic activity and undergo dramatic changes in gene expression and develop a complex senescence-associated secretory phenotype. Cellular senescence can compromise tissue repair and regeneration, thereby contributing toward aging. Removal of senescent cells can attenuate age-related tissue dysfunction and extend health span. Senescence can also act as a potent anti-tumor mechanism, by preventing proliferation of potentially cancerous cells. It is a cellular program which acts as a double-edged sword, with both beneficial and detrimental effects on the health of the organism, and considered to be an example of evolutionary antagonistic pleiotropy. Activation of the p53/p21WAF1/CIP1 and p16INK4A/pRB tumor suppressor pathways play a central role in regulating senescence. Several other pathways have recently been implicated in mediating senescence and the senescent phenotype. Herein we review the molecular mechanisms that underlie cellular senescence and the senescence associated growth arrest with a particular focus on why cells stop dividing, the stability of the growth arrest, the hypersecretory phenotype and how the different pathways are all integrated

Dynamic properties of silicon-integrated short-wavelength hybrid-cavity VCSEL

We present a vertical-cavity surface-emitting laser (VCSEL) where a GaAs-based "half-VCSEL" is attached to a dielectric distributed Bragg reflector on silicon using ultra-thin divinylsiloxane-bis-benzocyclobutene (DVS-BCB) adhesive bonding, creating a hybrid cavity where the optical field extends over both the GaAs- and the Si-based parts of the cavity. A VCSEL with an oxide aperture diameter of 5 mu m and a threshold current of 0.4 mA provides 0.6 mW output power at 845 nm. The VCSEL exhibits a modulation bandwidth of 11 GHz and can transmit data up to 20 Gbps

Genetic variability studies in segregating generation for grain and nutritional quality traits in rice (Oryza sativa L.)

The experimental materials used were four traditional landraces and six improved high yielding varieties of Tamil Nadu raised in during kharif 2012-2014. Genetic variability parameters on F3 population (20 selected F3 plants) of two cross combination viz., IR 72 x Veeradangan and ADT 39 x Kavuni in F3 population depicted wide range of variability and its ranged from 6.46 to 10.39 mg/100 g while it was from 5.39 to 7.65 mg/100 g in IR 72 x Veeradangan F3 population. Calcium content for IR 72 x Veeradangan in selected F3 population recorded wide range of variability and its ranged from 61.43 to 97.63 mg/100 g with a mean value of 80.67 mg/100 g whereas, ADT 39 x Kavuni in F3 population revealed the low range of variability and its ranged from 53.38 to 94.25 mg/100 g with a mean value of 79.58 mg/100 g for magnesium content. For iron content, IR 72 x Veeradangan in F3 population showed wide range of variability and its ranged from 0.53 to 1.03 mg/100 g with a grand mean of 0.80 mg/100 g whereas, ADT 39 x Kavuni in F3 population ranged from 0.61 to 1.33 mg/100 g and from with a grand mean value of 0.97 mg/100 g. For zinc content, wide range of variability was found in ADT 39 x Kavuni (1.43 to 2.16 mg/100 g) and in IR 72 x Veeradangan (1.51 to 1.98 mg/100 g) in F3 population

Marketing Behavior of Banana Grower in Bhagalpur District of Bihar

The study was conducted on primary data, collected from a sample of 60 banana growers, consisted of 26 (43%), 25 (42%) and 9 (15%) marginal & small, semi-medium and medium & large category. The data were collected from the sample growers with the help of specifically prepared pre-tested schedules through Survey Method by interviewing them, selected through Multi-Stage Sampling Technique from a cluster of 3 villages of Nawgachhia block of Bhagalpur district. The growers in general (76.67%) were found selling banana in ‘local market’. The semi-medium and medium & large category (36.0 and 56.0 per cent) growers were also found selling it to ‘distant markets’. The ‘contract sale’ was pre-dominantly prevailed as ‘mode of sale’ in the area. The ‘cash sale’ as-well-as ‘credit sale’ was prevailing in the area. The marginal & small category growers sold banana to the pre-harvest contractors